Tuesday, February 18, 2020

Commercial law Essay Example | Topics and Well Written Essays - 1750 words - 2

Commercial law - Essay Example Once the terms of an agency agreement have been made, it is important to draft a written contract that any of the parties involved can request, which would state the duration of the contract among other things. An agency agreement usually contains the fixed term of the contract, exists for an indefinite term that is terminable and lastly a fixed term that can be extended if agreed by both parties1. In relation to Rosie and Simon’s case, the parties did have a written contract or agency agreement that did not state the terms of their contract in detail. The implication of this is that it might be difficult for Simon to prove that Rosie went against the terms of the contract that they had agreed upon through the written agency agreement. Additionally, Rosie is in breach of the contract they agreed upon with Simon because she did not give Simon the 10% commission that they had agreed on when he sold a piece of work for her. In order for Simon to be safe, he would have made sure that he drafted a contract that captured much detail on how he was to make money out of the contract. For this reason, Rosie could be entitled to not pay Simon. On the contrary, the Commercial Agents regulation requires that either of the parties wishing to terminate an agreement entered for an indefinite period issue adequate notice to the other party, which Rosie did not comply. The regulation requires that a person provides notice of termination depending on the period they have been in the contract. For example, if they have been in the contract for a year, they should issue a one months’ notice, two years attracts a two months’ notice and so on. Therefore, Simon has grounds to seek compensation for the breaching of the contract that he had entered into with Rosie based on not being issued with proper notice. The regulation requires that a principal act dutifully to the agent and in good faith to which she did not

Monday, February 3, 2020

Contraction in Smooth Muscle Cells compared to Contraction in Skeletal Essay

Contraction in Smooth Muscle Cells compared to Contraction in Skeletal Muscle Cells - Essay Example In this assignment, based on studies, a comparison has been drawn between the contractions of these two types muscles at the cellular and molecular levels. Before going into this discussion, contraction must be defined. Contraction is defined by activation of the muscle fibers with a demonstrable shortening of the muscle fibers2. The physiological events in relation to muscle contraction have been delineated in great detail, and they reveal that basically, with neural stimulation there occurs a series of molecular events initiated by increase in the cytosolic calcium concentration. In this assignment, these events will be looked at in a greater detail to compare these events between the striated and nonstriated muscles. Each skeletal muscle is made up of a large number of skeletal muscle fibers, which are thin cylindrical multinucleated cells of variable length, which in turn are made up of myofibrils, which are bundles of filamentous structures running along the length of the fiber. While observing skeletal- or cardiac smooth muscle fibers through microscope, a series of light and dark bands perpendicular to the long axis of the fiber are very conspicuous. Actually, each myofibril consists of repeating sarcomeres, and the alignment of these sarcomeres3 between adjacent myofibrils gives rise to these bands in the skeletal muscle. The structural plan of the myofibril is such that the sarcomeres are placed end to end, and this fundamental contractile unit is visible within skeletal and cardiac muscles. On the contrary, smooth muscle cells do not show a banding pattern. Actually, the arrangement of sarcomeres leads to the striated pattern in skeletal and cardiac fibers, and sarcomeres in turn comprise of alternate arrangements of numerous thick and thin filaments in the cytoplasm to give rise to roughly 1-2 micrometer cylindrical bundles. Smooth muscles are abundant mainly in the visceral organs, such as, gut, blood vessels, bladder, and uterus, and they are to serve a particular function. For example, smooth muscles present in the sphincters are designed to maintain a steady contraction for long periods of time and then rapidly relax or in other muscles, they remain constantly activated. To suit these varied functions, the smooth muscles consists of sheets of many small spindle-shaped cells linked together by junctional contacts. Although these serve as mechanical continuity between adjacent spindles, actually, in places there are gap junctions that are designed to provide electrical continuity between cells. Each cell is uninucleated, shorter than striated muscles, and broader than a myofibril. Unlike striated muscle, no cross striations are visible, although they contain the same contractile protein filaments, actin and myosin. It is important to note that their arrangement is irregular in a loose lattice unlike th e regular arrangement of skeletal and smooth muscles. Myosin has been termed as a molecular motor. This consists of two heavy chains and two pairs of light chains. The two terminal ends of the heavy chains create a coil that aggregate in the cell to create the basic unit of a thick filament. The remainder of this molecule juts outward from the thick filament creating the cross-bridge. Thus, these polypeptides combine